913 results
Article

Anaplastic large cell lymphoma (ALK+/ALK-)

Anaplastic large cell lymphomas (ALCL) are group of mature T-cell lymphoma first described in 1985 as a large-cell neoplasm with anaplastic morphology immunostained by the Ki-1 antibody, which recognizes CD30. The WHO classification of haematolymphoid tumors recognizes three distinct entities: ...
Article

POEMS syndrome

POEMS syndrome is the acronymic name for a rare multisystem paraneoplastic disorder including the following features: P: polyneuropathy O: organomegaly E: endocrinopathy M: monoclonal gammopathy S: skin changes Clinical presentation The diagnostic criteria differ from the acronym. Accordi...
Case

Extramedullary hematopoiesis

  Diagnosis almost certain
Saikat Sarkar
Published 26 Aug 2016
60% complete
X-ray
Article

Myelodysplastic/myeloproliferative neoplasms

Myelodysplastic syndrome / myeloproliferative neoplasm (MDS/MPN) overlap syndromes refer to a group of chronic clonal myeloid malignancies in which there are features of both myelodysplastic syndrome and myeloproliferative neoplasm at the time of presentation. Entities that can fall into this g...
Case

Mediastinal lymphoma

  Diagnosis almost certain
Ayush Goel
Published 25 Oct 2013
83% complete
CT
Case

Felty syndrome

  Diagnosis almost certain
Maxymyshyn Nazar
Published 24 Mar 2023
80% complete
CT
Article

Leukemoid reaction

A leukemoid reaction refers to a marked increase in white blood cells (>50000 cells/mL), typically neutrophils, which manifests as an acute inflammatory reaction that can mimic leukemia. Pathology Leukemoid reactions often occur from accelerated release of cells from the bone marrow. Features...
Case

Extramedullary hematopoiesis

  Diagnosis certain
Faeze Salahshour
Published 07 Aug 2020
95% complete
Annotated image CT
Case

Angioimmunoblastic lymphoma

  Diagnosis certain
Matthew Tse
Published 09 Aug 2023
95% complete
CT
Article

Lymphomatoid granulomatosis (CNS manifestations)

Lymphomatoid granulomatosis of the central nervous system is uncommon, but represents the second most common site of involvement in patients with systemic lymphomatoid granulomatosis, after the lungs, which are most commonly involved. In the 2021 (5th edition) WHO classification of CNS tumors it...
Case

Renal lymphoma

  Diagnosis certain
Chris O'Donnell
Published 30 Nov 2018
87% complete
Fluoroscopy Ultrasound CT Pathology
Case

Multiple myeloma - pelvic radiograph

  Diagnosis almost certain
Andrew Dixon
Published 03 Jun 2010
69% complete
X-ray
Article

Lupus anticoagulant

Lupus anticoagulant refers to an immunoglobulin that binds to phospholipids and proteins associated with cell membranes. The name lupus "anticoagulant" is in fact a misnomer as it is a prothrombotic agent. Patients with lupus anticoagulant have a primary hypercoagulable state and a greater prope...
Case

H-shaped vertebrae - sickle cell disease

  Diagnosis almost certain
Mohamed Mahmoud Elthokapy
Published 08 Dec 2021
80% complete
CT
Case

Secondary pulmonary lymphoma

  Diagnosis almost certain
Khalid Alhusseiny
Published 01 Nov 2019
80% complete
CT
Case

Plasmacytoma - sacrum

  Diagnosis certain
Henry Knipe
Published 15 Jun 2023
83% complete
CT X-ray
Article

MALT lymphoma

Mucosa-associated lymphoid tissue (MALT) lymphoma, sometimes shortened to MALToma, is a type of low-grade extranodal lymphoma. Terminology In the 5th edition of the WHO classification of haematolymphoid tumors, it is a mature B-cell neoplasm termed extranodal marginal zone lymphoma of mucosa-a...
Article

Extramedullary hematopoiesis

Extramedullary hematopoiesis is a response to the failure of erythropoiesis in the bone marrow. This article aims to a general approach on the condition, for a dedicated discussion for a particularly involved organ, please refer to the specific articles on:  extramedullary hematopoiesis in the...
Case

Solitary bone plasmacytoma (PET-CT)

  Diagnosis almost certain
Artyom Artashesyan
Published 20 Dec 2021
79% complete
Nuclear medicine
Case

Extramedullary hematopoiesis - pelvic masses

  Diagnosis almost certain
Ramesh Giti
Published 18 Apr 2023
79% complete
Ultrasound

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