Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.

1,129 results
Article

Dedifferentiated chondrosarcoma

Dedifferentiated chondrosarcomas (DCS) are malignant high-grade chondrosarcomas with a poor prognosis. They have a bi-morphic histomorphology of conventional chondrosarcoma and a non-cartilaginous high-grade sarcoma. Epidemiology Dedifferentiated chondrosarcomas can develop in 10-15% of centra...
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Renal lymphoma

Renal lymphoma is usually a part component of multi-systemic lymphoma. Primary renal lymphoma is defined as lymphoma involving the kidney exclusively without any manifestation of extra-renal lymphatic disease 3-5. Typical imaging findings are multiple bilateral hypodense or infiltrative renal ma...
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Chondroblastoma vs clear cell chondrosarcoma

Distinguishing between a chondroblastoma and epiphyseal clear cell chondrosarcoma can be difficult and differences are listed. Epidemiology Both bone tumors have been reported at any age, but chondroblastomas are usually seen in the 2nd and early 3rd decade whereas clear cell chondrosarcomas h...
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CT abdomen-pelvis (protocol)

The CT abdomen-pelvis protocol serves as an outline for an examination of the whole abdomen including the pelvis. It is one of the most common CT protocols for any clinical questions related to the abdomen and/or in routine and emergencies. It forms also an integral part of trauma and oncologic ...
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Primary mediastinal large B-cell lymphoma

Primary mediastinal large B-cell lymphoma is a distinct entity, recognized in the WHO classification of lymphoma. Epidemiology Primary mediastinal large B-cell lymphoma accounts approximately 5% of large B-cell lymphoma, which is usually disseminated or found in the abdomen. There appears to b...
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Tumors of the small intestine

The small intestine is rarely the site of malignant tumors, although it accounts for ~75% of the entire length of the GI tract and more than 90% of the mucosal surface. Approximately 40 different histologic tumor types have been described.  In this article, an overview will be given of the most...
Article

HIV associated neoplasms

HIV-associated neoplasms are numerous and can be broadly divided into two groups: AIDS-defining malignancies associated but not AIDS defining malignancies AIDS-defining malignancies The development of these malignancies in HIV affected individuals generally implies progression to AIDS 4: Ka...
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Bilateral testicular lesions

Bilateral testicular lesions have a relatively limited differential diagnosis.  Differential diagnosis Neoplastic  lymphoblastic leukemia (acute or chronic) lymphoma (non-Hodgkin's) primary testicular lymphoma is rare but the testes are often the site of lymphoma/leukemia recurrence due to ...
Article

Skull metastases

Metastases to the skull are very common in patients with disseminated skeletal metastatic disease, although they are often asymptomatic. For a more detailed general discussion please refer to the article on skeletal metastatic disease. Epidemiology Skull metastases are seen in ~20% (range 15-2...
Article

Dysembryoplastic neuroepithelial tumor

Dysembryoplastic neuroepithelial tumors (DNET) are benign (WHO Grade 1) slow growing glioneuronal tumors arising from either cortical or deep grey matter. They are considered part of the heterogeneous group of tumors known as long-term epilepsy-associated tumors (LEATs). The vast majority of DN...
Article

Hemangioblastoma (central nervous system)

Hemangioblastomas are tumors of vascular origin and occur both sporadically and in patients with von Hippel Lindau disease. They are WHO grade 1 tumors, which can occur in the central nervous system or elsewhere in the body, including kidneys, liver, and pancreas. These tumors generally present...
Article

High-grade astrocytoma with piloid features

High-grade astrocytoma with piloid features (HGAP) is a rare tumor most commonly encountered in the posterior fossa of adults, especially those with neurofibromatosis type 1. It appears heterogeneous and has a relatively poor prognosis.  Epidemiology Due to the small number of patients reporte...
Article

Choledochal cyst

Choledochal cysts represent congenital cystic dilatations of the biliary tree. Diagnosis relies on excluding other conditions as a cause of biliary duct dilatation, e.g. tumor, gallstone, inflammation. Epidemiology Choledochal cysts are rare, with an incidence of 1:100,000-150,000. Although th...
Article

Brachytherapy

Brachytherapy, also known as sealed source radiotherapy or endocurietherapy, is a form of radiotherapy where a radioactive source is placed, under the guidance of imaging, within or next to the area requiring treatment. This provides localized targeted internal radiation. Brachytherapy has been...
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Soap bubble appearance (differential diagnosis)

Soap bubble appearance describes a multi-loculated bubbly appearance of lesion or structure. A soap bubble appearance of a bone lesion refers to: an expansile lytic lesion with internal trabeculations and preserved cortex, usually of benign nature  but may be used to describe more aggressive ...
Article

Renal osteodystrophy

Renal osteodystrophy, also known as uremic osteopathy, is a constellation of musculoskeletal abnormalities that occur in patients with chronic renal failure, due to concurrent and superimposed: osteomalacia (adults) or rickets (children) secondary hyperparathyroidism: abnormal calcium and phos...
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Labeled imaging anatomy cases

This article lists a series of labeled imaging anatomy cases by body region and modality. Brain CT head: non-contrast axial CT head: non-contrast coronal CT head: non-contrast sagittal CT head: non-contrast axial with clinical questions CT head: angiogram axial CT head: angiogram coronal ...
Article

Omental cake

Omental cake refers to infiltration of the omental fat by material of soft-tissue density. The appearances refer to the contiguous omental mass simulating the top of a cake. Masses on the peritoneal surfaces and malignant ascites may also be present.  Pathology The most common cause is metasta...
Article

External beam radiotherapy

External beam radiotherapy (EBRT) (also known as teletherapy) is a form of ionizing radiation therapy delivered by a medical linear accelerator (or historically a cobalt-60 source) to a patient lying on a treatment bed. Megavoltage x-rays (4-25 MV) are the most commonly used. Alternative forms o...
Article

Rotational/helical/arc intensity-modulated radiation therapy

Rotational/helical/arc intensity-modulated radiation therapy (IMRT) is the most advanced form of IMRT is conceptually similar to helical or cone-beam CT 1. The radiation beam remains turned on throughout the treatment while the gantry is moved around the patient at variable speed and the multi-l...

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