Taylor dysplasia is a type of focal cortical dysplasia and a common cause of refractory epilepsy. Under both the Palmini classification and the more recent Blumcke classification of focal cortical dysplasia, Taylor dysplasia is classified as type II.
For further discussion of the radiographic features please refer to the parent article: focal cortical dysplasia.
Taylor dysplasia is determined histologically due to the presence of certain features such as giant neurones, dysmorphic neurons with or without balloon cells 4,7. The latter further divides FCDT into two main subtypes 2,7.
- type IIa: no balloon cells
- type IIb: balloon cells present
History and etymology
Taylor dysplasia is named after David C. Taylor, a British psychiatrist who first described it in 1971 5.
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- 6. Colombo N, Tassi L, Galli C et-al. Focal cortical dysplasias: MR imaging, histopathologic, and clinical correlations in surgically treated patients with epilepsy. AJNR Am J Neuroradiol. 2003;24 (4): 724-33. AJNR Am J Neuroradiol (full text) - Pubmed citation
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