Widespread osteonecrosis - sickle cell disease
Presentation
Chronic pain at multiple joints; known case of sickle cell disease.
Patient Data
Age: 30 years
Gender: Female
From the case:
Widespread osteonecrosis - sickle cell disease
MRI
Knee joint
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Coronal T2 fat sat
Medullary metaphyseal lesions at the distal femur and proximal tibia, showing serpiginous borders with double-line sign (bone infarcts).
Subchondral avascular necrosis (AVN) of the femoral condyles.
From the case:
Widespread osteonecrosis - sickle cell disease
MRI
Shoulder joint
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Coronal T1
Subchondral avascular necrosis (AVN) of the humeral head.
From the case:
Widespread osteonecrosis - sickle cell disease
MRI
Both hip joints
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Coronal STIR
Subchondral avascular necrosis (AVN) of both femoral heads, with early structural collapse of the right femoral head.
Case Discussion
Sickle cell disease is one of the most common causes of widespread osteonecrosis including bone infarcts and subchondral AVN.
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