Articles
Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and continuously improved upon by countless contributing members. Our dedicated editors oversee each edit for accuracy and style. Find out more about articles.
1,118 results found
Article
Atypical teratoid/rhabdoid tumor
Atypical teratoid/rhabdoid tumors (AT/RT) are uncommon WHO grade 4 tumors, which in the vast majority of cases occurs in young children less than two years of age. It most frequently presents as a posterior fossa mass. AT/RT often resembles medulloblastoma by imaging and even H&E microscopy, and...
Article
Vertebra plana
Vertebra plana (plural: vertebrae planae), also known as the pancake, silver dollar or coin-on-edge vertebra, is the term given when a vertebral body has lost almost its entire height anteriorly and posteriorly, representing a very advanced compression fracture.
Pathology
It can occur in a var...
Article
Radiogenomics
Radiogenomics denotes the relationship between the imaging features of a particular disease and various genetic or molecular features. The former is referred to as an imaging phenotype, whereas the later as genomic phenotype.
Radiogenomics, therefore, provides a tool for clinicians to correlat...
Article
Renal cell carcinoma (TNM staging)
The TNM system may be used for staging of renal cell carcinoma. An older but still widely used system for staging of renal cell carcinoma in some practices is the Robson staging system.
TNM staging (8th edition)
Primary tumor staging (T)
Tx: tumor cannot be assessed
T0: tumor not seen
T1
T...
Article
Whole-body diffusion-weighted MRI
Whole-body diffusion-weighted MRI (WB-MRI) is an advanced imaging technique that combines anatomical and functional MRI sequences to provide a comprehensive assessment of the whole-body in a single examination.
WB-MRI uses the properties of diffusion-weighted imaging for oncological disease sta...
Article
Ann Arbor staging system (historical)
The Ann Arbor staging system was the landmark lymphoma staging classification system for both Hodgkin lymphoma and non-Hodgkin lymphoma. It is named after the town of Ann Arbor in the US state of Michigan where the Committee on Hodgkin's Disease Staging Classification met in 1971 to agree on it....
Article
Adenocarcinoma (urinary bladder)
Adenocarcinoma of the urinary bladder is rare and accounts for only ~1% of all bladder cancers (90% are transitional cell carcinomas).
Pathology
Metaplasia of urinary bladder induced by chronic irritation or infection can lead to adenocarcinoma. Pathological types of adenocarcinoma of the urin...
Article
Solid periosteal reaction
Solid periosteal pattern is thought to evolve from single layer and multilayered periosteal reactions, forming a solid layer of mature new bone adjacent to the cortex. It denotes a longstanding pathological process.
Differential diagnosis
osteoid osteoma
osteomyelitis
osteosarcoma
chondrosa...
Article
Pancreatic acinar cell carcinoma
Pancreatic acinar cell carcinomas are rare exocrine neoplasms that comprise ~1% of all pancreatic tumors. This tumor shows more aggressive behavior than the far more common adenocarcinoma 1,3,4.
Epidemiology
This tumor is most common in pediatric (8-15 years) and adult (60 years) populations. ...
Article
Bone marrow
Bone marrow is ubiquitous throughout the skeleton, primarily composed of hematopoietic cells and fat cells between bony trabeculae and fibrous retinacula. It performs numerous physiological functions and dynamically changes during normal aging and in response to stressors and pathology. Although...
Article
Pancreatic mesenchymal neoplasms
Pancreatic mesenchymal neoplasms, or pancreatic nonepithelial neoplasms, are a group of rare pancreatic neoplasms that arise from the structural elements of the pancreas (nerves, fat, lymph), rather than from the exocrine or endocrine cells of the pancreas. Neoplasms from exocrine and endocrine ...
Article
Inflammatory leiomyosarcoma
Inflammatory leiomyosarcomas are malignant tumors with smooth muscle differentiation and a prominent inflammatory infiltrate that were recognized as a distinct entity by the WHO in 2020 1-3.
Epidemiology
Inflammatory leiomyosarcomas are very rare lesions with most cases seen in adults with a p...
Article
Terminal ileitis (differential)
The differential diagnosis for a terminal ileitis is quite extensive, and includes:
inflammatory bowel disease
Crohn disease (most common)
backwash ileitis due to ulcerative colitis
infectious colitis
Yersinia spp.
Yersinia enterocolitica
Yersinia pseudotuberculosis
Salmonella spp.
Sa...
Article
Siewert-Stein classification of esophageal adenocarcinoma
The Siewert-Stein classification of esophageal adenocarcinoma classes tumors of the gastro-esophageal junction according to the relationship between the epicenter of the tumor and the gastro-esophageal junction 1. The classification system was initially proposed by Siewert et al in 1996, becomin...
Article
Whitmore-Jewett staging system (historical)
The Whitmore-Jewett staging system (also known as the Jewett staging system or ABCD system) is a superseded staging system for prostate cancer. It was developed by the American Urological Association (AUA). Most societies (including AUA) and clinicians now advocate and use the TNM staging system...
Article
Adenoma-carcinoma sequence
The adenoma-carcinoma sequence refers to a stepwise pattern of mutational activation of oncogenes (e.g. K-ras) and inactivation of tumor suppressor genes (e.g. p53) that results in cancer. An oncogene is a gene that has the potential to cause cancer. In tumor cells, these are often mutated or ex...
Article
Percutaneous endoscopic gastrostomy
Percutaneous endoscopic gastrostomy (PEG) is a procedure where a flexible feeding tube (commonly known as a PEG tube) is inserted through the abdominal wall and into the stomach via endoscopy. Alternatively a tube can be placed under radiological guidance, known as a radiologically inserted gast...
Article
Radiologically inserted gastrostomy (RIG)
A Radiologically inserted gastrostomy (RIG), or percutaneous radiological gastrostomy (RPG), is a procedure where a gastrostomy tube is inserted percutaneously into the stomach under fluoroscopic guidance, principally to provide nutritional support for patients with swallowing disorders 1. Gastr...
Article
Neonatal neuroblastoma
Neonatal neuroblastoma is a type of congenital neuroblastoma, an embryonal tumor arising from the sympathetic nervous system. In the majority of cases (45%), the tumor is localized in the adrenal gland.
Epidemiology
Neonatal neuroblastoma accounts for less than 5% of all cases and carries a f...
Article
Neuroblastoma (staging)
There are two methods of neuroblastoma staging; the International Neuroblastoma Risk Group Staging System (INRGSS, based on imaging of pre-treatment patients), and the International Neuroblastoma Staging System (INSS, based on the outcomes of surgery).
International Neuroblastoma Risk Group St...
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