Lesions of the corpus callosum

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Lesions of the corpus callosum (differential)

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Lesions of the corpus callosum, or callosal lesions can be classified into those without mass lesions and invading mass lesions. Typically only aggressive lesions can invade the corpus callosum as it is composed of very dense white matter tracts which act like a barrier to tumour spreading ¹.

The differential diagnosis for a corpus callosum lesion can include:

primary CNS lymphoma
glioblastoma (butterfly glioma)
anaplastic astrocytoma
multiple sclerosis
- neuromyelitis optica (NMO)
acute disseminated encephalomyelitis
progressive multifocal leukoencephalopathy (PML)
gliomatosis cerebri
diffuse axonal injury
enlarged perivascular spaces
transient lesion of the splenium
callosal oligodendroglioma
corpus callosum impingement syndrome
arteriovenous malformation around the corpus callosum
Marchiafava-Bignami disease: demyelination and necrosis can appear as cystic lesions
tubonodular pericallosal lipoma: associated with dysgenesis of the corpus callosum
Susac syndrome
infarction ³
metachromatic leukodystrophy
X-Linked adrenoleukodystrophy

~~-<li><a href="/articles/acute-disseminated-encephalomyelitis">acute disseminated encephalomyelitis</a></li>~~
+<li><a href="/articles/acute-disseminated-encephalomyelitis-adem-1">acute disseminated encephalomyelitis</a></li>

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Lesions of the corpus callosum

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