Technetium-99m agents
Updates to Article Attributes
Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. A radiopharmaceutical labelled with Tc-99m constitutes a co-ordination complex in which ligands bond to a central atom of Tc-99m by co-ordinate covalent bonds 4 .
The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific radiopharmaceuticals and optimise the functional imaging of various structures:
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thyroid imaging
Meckel scan
testicular scintigraphy
parathyroid subtraction study
gastric emptying, intestinal and rectal functional studies
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splenic and hepatic imaging
taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow
bone marrow and soft tissue infection scintigraphy
lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy
technetium-99m MDP or HDP: bone scintigraphy
technetium-99m MAA: lung perfusion imaging
technetium-99m teboroxime: cardiac imaging
-
technetium-99m mebrofenin:
hepatobilliary scintigraphy
liver function analysis
-
cardiac imaging
parathyroid imaging
technetium-99m HIDA : hepatobiliary scintigraphy
technetium-99m ECD: CNS imaging
technetium-99m HMPAO: cerebral perfusion imaging
technetium-99m HMPAO labelled WBC: infection scintigraphy
technetium-99m
labeledlabelled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis-
assessment of occult gastrointestinal haemorrhage
assessment of vascular lesions, e.g. hepatic haemangioma
assessment of cardiac function, first pass or equilibrium
technetium-99m labelled heat-denatured RBC: specific splenic assessment, gold standard in splenosis
technetium-99m MAG3: renal imaging
technetium-99m DMSA: renal cortical imaging
-
glomerular renal imaging
glomerular filtration rate
-
technetium-99m DTPA (aerosol):
lung ventilation imaging
bronchial clearance
-
Lung ventilation imaging
technetium-99m GHA: oncological imaging (e.g. low-grade glioma, lung)
-<a href="/articles/tc-99m-pertechnetate">technetium-99m pertechnetate</a><ul>-<li>thyroid imaging</li>-<li>Meckel scan</li>-<li>testicular scintigraphy</li>-<li>parathyroid subtraction study</li>-<li>gastric emptying, intestinal and rectal functional studies</li>- +<p><a href="/articles/tc-99m-pertechnetate">technetium-99m pertechnetate</a></p>
- +<ul>
- +<li><p>thyroid imaging</p></li>
- +<li><p>Meckel scan</p></li>
- +<li><p>testicular scintigraphy</p></li>
- +<li><p>parathyroid subtraction study</p></li>
- +<li><p>gastric emptying, intestinal and rectal functional studies</p></li>
-<a href="/articles/tc-99m-sulfur-colloid-4">technetium-99m sulfur colloid</a><ul>-<li>splenic and hepatic imaging</li>-<li>taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow</li>-<li>bone marrow and soft tissue infection scintigraphy</li>-<li>lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy</li>- +<p><a href="/articles/tc-99m-sulfur-colloid-4">technetium-99m sulfur colloid</a></p>
- +<ul>
- +<li><p>splenic and hepatic imaging</p></li>
- +<li><p>taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow</p></li>
- +<li><p>bone marrow and soft tissue infection scintigraphy</p></li>
- +<li><p>lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy</p></li>
- +<li><p><a href="/articles/technetium-99m-methyl-diphosphonate">technetium-99m MDP or HDP</a>: bone scintigraphy</p></li>
- +<li><p><a href="/articles/tc-99m-maa">technetium-99m MAA</a>: lung perfusion imaging</p></li>
- +<li><p><a href="/articles/tc-99m-teboroxime">technetium-99m teboroxime</a>: cardiac imaging</p></li>
- +<li><p><a href="/articles/technetium-99m-pyrophospahate">technetium-99m pyrophosphate</a>: <a href="/articles/cardiac-amyloid">cardiac amyloid</a><a href="/articles/cardiac-amyloidosis">osis</a> imaging</p></li>
-<a href="/articles/technetium-99m-methyl-diphosphonate">technetium-99m MDP or HDP</a>: bone scintigraphy</li>-<li>-<a href="/articles/tc-99m-maa">technetium-99m MAA</a>: lung perfusion imaging</li>-<li>-<a href="/articles/tc-99m-teboroxime">technetium-99m teboroxime</a>: cardiac imaging</li>-<li>-<a href="/articles/technetium-99m-pyrophospahate">technetium-99m pyrophosphate</a>: <a href="/articles/cardiac-amyloid">cardiac amyloid</a><a href="/articles/cardiac-amyloidosis">osis</a> imaging</li>-<li>technetium-99m mebrofenin:<ul>-<li>hepatobilliary scintigraphy</li>-<li>liver function analysis</li>- +<p>technetium-99m mebrofenin:</p>
- +<ul>
- +<li><p>hepatobilliary scintigraphy</p></li>
- +<li><p>liver function analysis</p></li>
-<a href="/articles/tc-99m-mibi">technetium-99m sestamibi/MIBI</a><ul>-<li>cardiac imaging</li>-<li>parathyroid imaging</li>- +<p><a href="/articles/tc-99m-sestamibi" title="Tc-99m sestamibi">technetium-99m sestamibi/MIBI</a></p>
- +<ul>
- +<li><p>cardiac imaging</p></li>
- +<li><p>parathyroid imaging</p></li>
- +<li><p><a href="/articles/technetium-99m-hida">technetium-99m HIDA</a> : hepatobiliary scintigraphy</p></li>
- +<li><p><a href="/articles/tc-99m-ecd">technetium-99m ECD</a>: CNS imaging</p></li>
- +<li><p><a href="/articles/tc-99m-hmpao">technetium-99m HMPAO</a>: cerebral perfusion imaging</p></li>
- +<li><p><a href="/articles/tc-99m-hmpao-labelled-wbc">technetium-99m HMPAO labelled WBC</a>: infection scintigraphy</p></li>
- +<li><p>technetium-99m labelled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis</p></li>
-<a href="/articles/technetium-99m-hida">technetium-99m HIDA</a> : hepatobiliary scintigraphy</li>-<li>-<a href="/articles/tc-99m-ecd">technetium-99m ECD</a>: CNS imaging</li>-<li>-<a href="/articles/tc-99m-hmpao">technetium-99m HMPAO</a>: cerebral perfusion imaging</li>-<li>-<a href="/articles/tc-99m-hmpao-labelled-wbc">technetium-99m HMPAO labelled WBC</a>: infection scintigraphy</li>-<li>technetium-99m labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis</li>-<li>-<a href="/articles/scintigraphy-performed-with-tc-99m-labeled-rbcs">technetium-99m labelled RBCs</a><ul>-<li>assessment of occult gastrointestinal haemorrhage</li>-<li>assessment of vascular lesions, e.g. <a href="/articles/hepatic-haemangioma-3">hepatic haemangioma</a>-</li>-<li>assessment of cardiac function, first pass or equilibrium</li>- +<p><a href="/articles/scintigraphy-performed-with-tc-99m-labeled-rbcs">technetium-99m labelled RBCs</a></p>
- +<ul>
- +<li><p>assessment of occult gastrointestinal haemorrhage</p></li>
- +<li><p>assessment of vascular lesions, e.g. <a href="/articles/hepatic-haemangioma-3">hepatic haemangioma</a></p></li>
- +<li><p>assessment of cardiac function, first pass or equilibrium</p></li>
-<li>technetium-99m labelled heat-denatured RBC: specific splenic assessment, <a href="/articles/gold-standard">gold standard</a> in <a href="/articles/splenosis">splenosis</a>-</li>- +<li><p>technetium-99m labelled heat-denatured RBC: specific splenic assessment, <a href="/articles/gold-standard">gold standard</a> in <a href="/articles/splenosis">splenosis</a></p></li>
- +<li><p><a href="/articles/tc-99m-mag3">technetium-99m MAG3</a>: renal imaging</p></li>
- +<li><p><a href="/articles/tc-99m-dmsa">technetium-99m DMSA</a>: renal cortical imaging</p></li>
-<a href="/articles/tc-99m-mag3">technetium-99m MAG3</a>: renal imaging</li>-<li>-<a href="/articles/tc-99m-dmsa">technetium-99m DMSA</a>: renal cortical imaging</li>-<li>-<a href="/articles/tc-99m-dtpa">technetium-99m DTPA</a>:<ul>-<li>glomerular renal imaging</li>-<li>glomerular filtration rate</li>- +<p><a href="/articles/tc-99m-dtpa">technetium-99m DTPA</a>:</p>
- +<ul>
- +<li><p>glomerular renal imaging</p></li>
- +<li><p>glomerular filtration rate</p></li>
-<a href="/articles/tc-99m-dtpa-aerosol">technetium-99m DTPA (aerosol)</a>:<ul>-<li>lung ventilation imaging</li>-<li>bronchial clearance</li>- +<p><a href="/articles/tc-99m-dtpa-aerosol">technetium-99m DTPA (aerosol)</a>:</p>
- +<ul>
- +<li><p>lung ventilation imaging</p></li>
- +<li><p>bronchial clearance</p></li>
-<a title="Technegas" href="/articles/technegas">Technegas</a>:<ul><li>Lung ventilation imaging</li></ul>- +<p><a href="/articles/technegas" title="Technegas">Technegas</a>:</p>
- +<ul><li><p>Lung ventilation imaging</p></li></ul>
-<li>-<a href="/articles/technetium-99m-gha">technetium-99m GHA</a>: oncological imaging (e.g. low-grade glioma, lung)</li>- +<li><p><a href="/articles/technetium-99m-gha">technetium-99m GHA</a>: oncological imaging (e.g. low-grade glioma, lung)</p></li>
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