Salivary gland tumors
Updates to Article Attributes
Body
was changed:
Salivary gland tumours can be very are variable in location, origin and malignant potential. In
Pathology
In general, the ratio of benign to malignant tumours is proportional to the gland size; ie: the parotid gland tends tends to have benign neoplamsneoplasm, the submandibular gland 50 50:50 and the sublingual glands and and accessory glands mostly malignant. Due to the size discrepancy in absolute numbers parotid gland has the most tumours.
FrequencyLocation
- parotid gland
- 70: 70% - minor salivary glands (including sublingual)
- 22: 22%(palatewith the palate being most frequent) - see(see: minor salivary gland tumours) - submandibular gland
- 8: 8%
Overall approximately 80~80% of all parotid masses are benign, and the majority of these are pleomorphic adenomas
Subtypes
Benign
- epithelial
-
pleomorphic adenoma
- this: this is the most common (≈ 50%) tumour of the parotid -
Warthin tumour
- essentially: essentially only found in the parotid, in older, usually male, patients; it is bilateral in 10-15% - intraductal papiloma of salivary glands
- oncocytoma of salivary glands
-
myoepithelioma: until recently considered a
sub typesubtype of pleomorphic adenoma; they can also originate in breast and bronchus
Benign
-
mucoepidermoid carcinoma
(commonest: most of the malignant lesions) - adenoid cystic carcinoma
- myoepithelioma
- adenocarcinoma (not otherwise specified)
- acinic cell carcinoma of salivary glands
- squamous cell carcinoma
ofof salivary glands -
malignant mixed tumours of the salivary glands
- carcinoma ex pleomorphic adenoma
- carcinosarcoma (true mixed tumour of the salivary glands)
- metastasising pleomorphic adenoma
-
metastases (mostly to intraparotid lymph nodes) 5
- cutaneous squamous cell carcinoma
- malignant melanoma
-
lymphoma (rare)
- primary: arising from the parotid gland as a MALToma6
- secondary: involving the intraparotid lymph nodes 6
See also
-<p><strong>Salivary gland tumours</strong> can be very variable. In general, the ratio of benign to malignant tumours is proportional to the gland size; ie: the <a href="/articles/parotid-gland">parotid gland</a> tends to have benign neoplams, the <a href="/articles/submandibular-gland">submandibular gland</a> 50:50 and the <a href="/articles/sublingual-gland">sublingual glands</a> and accessory glands mostly malignant. Due to the size discrepancy in absolute numbers parotid gland has the most tumours.</p><h5>Frequency</h5><ul>-<li>parotid gland - 70%</li>-<li>minor salivary glands (including sublingual) - 22% (palate being most frequent) - see <a href="/articles/minor-salivary-gland-tumours">minor salivary gland tumours</a>-</li>-<li>submandibular gland - 8%</li>-</ul><p>Overall approximately 80% of all parotid masses are benign, and the majority of these are pleomorphic adenomas</p><h4>Benign epithelial</h4><ul>- +<p><strong>Salivary gland tumours</strong> are variable in location, origin and malignant potential. </p><h4>Pathology</h4><p>In general, the ratio of benign to malignant tumours is proportional to the gland size; ie: the <a href="/articles/parotid-gland">parotid gland</a> tends to have benign neoplasm, the <a href="/articles/submandibular-gland">submandibular gland</a> 50:50 and the <a href="/articles/sublingual-gland">sublingual glands</a> and accessory glands mostly malignant. Due to the size discrepancy in absolute numbers parotid gland has the most tumours.</p><h5>Location</h5><ul>
- +<li>parotid gland: 70%</li>
- +<li>minor salivary glands (including sublingual): 22% with the palate being most frequent (see: <a href="/articles/minor-salivary-gland-tumours">minor salivary gland tumours</a>)</li>
- +<li>submandibular gland: 8%</li>
- +</ul><p>Overall ~80% of all parotid masses are benign, and the majority of these are pleomorphic adenomas</p><h5>Subtypes</h5><h6>Benign</h6><ul>
- +<li>
- +<strong>epithelial</strong><ul>
-<a href="/articles/pleomorphic-adenoma-of-the-salivary-glands">pleomorphic adenoma</a> - this is the most common (≈ 50%) tumour of the parotid</li>- +<a href="/articles/pleomorphic-adenoma-of-the-salivary-glands">pleomorphic adenoma</a>: this is the most common (≈ 50%) tumour of the parotid</li>
-<a href="/articles/warthin-tumour">Warthin tumour</a> - essentially only found in the parotid, in older, usually male, patients; it is bilateral in 10-15%</li>- +<a href="/articles/warthin-tumour">Warthin tumour</a>: essentially only found in the parotid, in older, usually male, patients; it is bilateral in 10-15%</li>
-<a href="/articles/myoepithelioma">myoepithelioma</a> : until recently considered a sub type of pleomorphic adenoma ; they can also originate in breast and bronchus</li>-</ul><h4>Benign non-epithelial</h4><ul>- +<a href="/articles/myoepithelioma">myoepithelioma</a>: until recently considered a subtype of pleomorphic adenoma; they can also originate in breast and bronchus</li>
- +</ul>
- +</li>
- +<li>
- +<strong>non-epithelial</strong><ul>
-</ul><h4>Malignant</h4><ul>- +</ul>
- +</li>
- +</ul><h6>Malignant</h6><ul>
-<a href="/articles/mucoepidermoid-carcinoma-of-salivary-glands">mucoepidermoid carcinoma </a>(commonest of the malignant lesions)</li>- +<a href="/articles/mucoepidermoid-carcinoma-of-salivary-glands">mucoepidermoid carcinoma</a>: most of the malignant lesions</li>
-<li><a href="/articles/squamous-cell-carcinoma-of-salivary-glands">squamous cell carcinoma of salivary glands</a></li>- +<li><a href="/articles/squamous-cell-carcinoma-of-salivary-glands">squamous cell carcinoma of salivary glands</a></li>
- +<li>metastases (mostly to intraparotid lymph nodes) <sup>5</sup><ul>
- +<li>cutaneous squamous cell carcinoma</li>
- +<li><a title="Malignant melanoma" href="/articles/malignant-melanoma">malignant melanoma</a></li>
- +</ul>
- +</li>
- +<li>lymphoma (rare)<ul>
- +<li>primary: arising from the parotid gland as a <a title="MALToma" href="/articles/malt-lymphoma">MALToma</a> <sup>6</sup>
- +</li>
- +<li>secondary: involving the intraparotid lymph nodes <sup>6</sup>
- +</li>
- +</ul>
- +</li>
References changed:
- 6. Robert Hermans. Head and Neck Cancer Imaging. (2012) ISBN: 9783642178689 - <a href="http://books.google.com/books?vid=ISBN9783642178689">Google Books</a>
- 5. Bron L, Traynor S, McNeil E, O'Brien C. Primary and Metastatic Cancer of the Parotid: Comparison of Clinical Behavior in 232 Cases. Laryngoscope. 2003;113(6):1070-5. <a href="https://doi.org/10.1097/00005537-200306000-00029">doi:10.1097/00005537-200306000-00029</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/12782825">Pubmed</a>
Sections changed:
- Gamuts
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