Submandibular gland enlargement

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Submandibular gland enlargement refers to an increase in the volume of the submandibular gland, exceeding normal values of 7.4 ± 1.8 cc ¹.

Obstructive causesPathology

Causes

Obstruction

sialolithiasis
submandibular duct stenosis (e.g. tumour, granulomatous disease)

~~Infections~~

Infection

acute sialadenitis ~~- following~~: following sialolithiasis
acute suppurative sialadenitis (submandibular abscess)
- from odontogenic infection
- from haematogenous spread
- immunodeficiency
acute viral sialadenitis
- mumps

Inflammatory

chronic sialadenitis
- Mikulicz syndrome
- Sjogren syndrome
- chronic sclerosing sialadenitis ~~- K~~: Küttner tumour
IgG4-related disease -: diffuse submandibular gland enlargement, with a homogeneous density ²
Granulomatosis with polyangiitis - Wegener granulomatosis ³
submandibular gland sarcoidosis ⁴ - rare

Neoplastic

All salivary gland tumours are to be considered

benign
malignant

Miscellaneous

bulimia nervosa -: painless diffuse swelling of major salivary glands¹
acromegaly ⁵

compensatory hypertrophy in the setting of contralateral congenital absence ⁶

-<p><strong>Submandibular gland enlargement</strong> refers to an increase in the volume of the <a href="/articles/submandibular-gland">submandibular gland</a>, exceeding normal values of 7.4 ± 1.8 cc <sup>1</sup></p><h4>Obstructive causes</h4><ul>
+<p><strong>Submandibular gland enlargement</strong> refers to an increase in the volume of the <a href="/articles/submandibular-gland">submandibular gland</a>, exceeding normal values of 7.4 ± 1.8 cc <sup>1</sup>.</p><h4>Pathology</h4><h5>Causes</h5><h6>Obstruction</h6><ul>
~~-</ul><h4>Infections</h4><ul>~~
+</ul><h6>Infection</h6><ul>
~~-<a href="/articles/acute-sialadenitis">acute sialadenitis</a> - following <a href="/articles/sialolithiasis">sialolithiasis </a>~~
+<a href="/articles/acute-sialadenitis">acute sialadenitis</a>: following <a href="/articles/sialolithiasis">sialolithiasis </a>
~~-</ul><h4>Inflammatory</h4><ul>~~
+</ul><h6>Inflammatory</h6><ul>
~~-<a href="/articles/kuttner-tumour">chronic sclerosing sialadenitis</a> - Küttner tumour</li>~~
+<a href="/articles/kuttner-tumour">chronic sclerosing sialadenitis</a>: Küttner tumour</li>
~~-<a href="/articles/igg4-related-disease">IgG4-related disease</a> - diffuse submandibular gland enlargement, with a homogeneous density <sup>2</sup>~~
+<a href="/articles/igg4-related-disease">IgG4-related disease</a>: diffuse submandibular gland enlargement, with a homogeneous density <sup>2</sup>
~~-</ul><h4>Neoplastic</h4><p>All <a href="/articles/salivary-gland-tumours">salivary gland tumours</a> are to be considered</p><ul>~~
+</ul><h6>Neoplastic</h6><p>All <a href="/articles/salivary-gland-tumours">salivary gland tumours</a> are to be considered</p><ul>
~~-</ul><h4>Miscellaneous</h4><ul>~~
+</ul><h6>Miscellaneous</h6><ul>
~~-<a href="/articles/bulimia-nervosa">bulimia nervosa</a> - painless diffuse swelling of <a href="/articles/major-salivary-glands">major salivary glands</a><sup>1</sup>~~
+<a href="/articles/bulimia-nervosa">bulimia nervosa</a>: painless diffuse swelling of <a href="/articles/major-salivary-glands">major salivary glands</a> <sup>1</sup>
+<li>compensatory hypertrophy in the setting of contralateral congenital absence <sup>6</sup>
+</li>

References changed:

6. Srinivasan A, Moyer J, Mukherji S. Unilateral Submandibular Gland Aplasia Associated with Ipsilateral Sublingual Gland Hypertrophy. AJNR Am J Neuroradiol. 2006;27(10):2214-6. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977216">PMC7977216</a> - <a href="https://www.ncbi.nlm.nih.gov/pubmed/17110697">Pubmed</a>

Images Changes:

Image 8 CT (C+ portal venous phase) ( create )

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