Technetium-99m agents
Updates to Article Attributes
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was changed:
Technetium agents based on the Technetium-99m (Tc-99m) radioisotope are frequently used agent in medical imaging. The radioactive technetium can be chelated to a number of different compounds to create specific radiopharmaceuticals and optimise imaging of various structures:
- Tc-99m ECD (ethyl cysteinate dimer) and Tc-99m HMPAO: CNS imaging
- Tc-99 GHA : Brain tumors (low-grade glioma)
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Tc-99m sulphur colloid
- splenic and hepatic imaging
- taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow
- bone marrow and soft tissue infection scintigraphy
- lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy
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Tc-99m pertechnetate
- thyroid imaging: Hyperthyroidism Vs thyroiditis,
- Meckel scan : for Meckel's diverticulum
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testicletesticular scan imaging: Rule out torsion Vs acute epididymo-orchitis - in dual phase parathyroid substraction imaging : for distinguishing from thyroid gland
- Tc-99m labeled with sulfur colloid used in gastric emptying studies, intestinal and rectal functional studies
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Tc-99m MDP:
bone imagingBone scans in wholebody onclogical/non-oncological conditions - Tc-99m MAA: lung perfusion imaging and Tc-99 DTPA (aerosol) for lung ventilation (as part of ventilation perfusion scintigraphy) to rule out Pulmonary embolism
- Tc-99m teboroxime: cardiac imaging
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Tc-99m
metforminMIBI: cardiac- cardiac imaging
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parathyroid imaging
1
- Tc-99m HMPAO: cerebral perfusion imaging (SPECT)
- Tc-99m HMPAO labelled WBC: infection scintigraphy
Tc-99m-labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis
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Tc-99m MIBIcardiac imagingparathyroid imaging
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Tc-99m labelled RBC
- assessment of occult gastrointestinal haemorrhage
- assessment of vascular lesions, e.g. hepatic haemangioma
- assessment of cardiac function, first pass or equilibrium
- 99mTc labeled heat-denatured RBC: specific splenic assessment, gold-standard in splenosis
- Tc-99m MAG3: Tubular renal imaging agent. Measures ERPF
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Tc-99m DMSA:
renalRenal cortical imaging for assessment of acute pyelonephritis,parenchymal studiescortical scarring, ectopic kidney - Tc-99m DTPA: Glomerular renal imaging agent, measures camera based glomerular filtration ratio
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Tc-99m DTPA (aerosol(GFR) by Gates method. Another method is plasma sample method (cumbersome but reliable): lung ventilation imaging, bronchial clearance -
Tc-99m sestamibi: parathyroid imaging
-<a href="/articles/tc-99m-ecd">Tc-99m ECD</a> (ethyl cysteinate dimer): CNS imaging</li>- +<a href="/articles/tc-99m-ecd">Tc-99m ECD</a> (ethyl cysteinate dimer) and Tc-99m HMPAO: CNS imaging</li>
- +<li>Tc-99 GHA : Brain tumors (low-grade glioma)</li>
-<li>thyroid imaging</li>-<li>Meckel scan</li>-<li>testicle imaging</li>-<li>in parathyroid imaging for distinguishing from thyroid gland</li>-<li>gastric emptying studies, intestinal and rectal functional studies</li>- +<li>thyroid imaging: Hyperthyroidism Vs thyroiditis, </li>
- +<li>Meckel scan : for Meckel's diverticulum</li>
- +<li>testicular scan imaging: Rule out torsion Vs acute epididymo-orchitis</li>
- +<li>in dual phase parathyroid substraction imaging : for distinguishing from thyroid gland</li>
- +<li>Tc-99m labeled with sulfur colloid used in gastric emptying studies, intestinal and rectal functional studies</li>
-<a href="/articles/technetium-99m-methyl-diphosphonate">Tc-99m MDP</a>: bone imaging</li>- +<a href="/articles/technetium-99m-methyl-diphosphonate">Tc-99m MDP</a>: Bone scans in wholebody onclogical/non-oncological conditions </li>
-<a href="/articles/tc-99m-maa">Tc-99m MAA</a>: lung perfusion imaging</li>- +<a href="/articles/tc-99m-maa">Tc-99m MAA</a>: lung perfusion imaging and Tc-99 DTPA (aerosol) for lung ventilation (as part of ventilation perfusion scintigraphy) to rule out Pulmonary embolism</li>
-<a href="/articles/tc-99m-metroformin">Tc-99m metformin</a>: cardiac imaging <sup>1</sup>-</li>- +<a href="/articles/tc-99m-mibi">Tc-99m MIBI</a><ul>
- +<li>cardiac imaging</li>
- +<li>parathyroid imaging : For parathyroid adenoma</li>
- +</ul>Tc-99m HIDA : Hepatobiliary scintigraphy</li>
-<a href="/articles/tc-99m-mibi">Tc-99m MIBI</a><ul>-<li>cardiac imaging</li>-<li>parathyroid imaging</li>-</ul>-</li>-<li>-<a href="/articles/tc-99m-mag3">Tc-99m MAG3</a>: renal imaging</li>-<li>-<a href="/articles/tc-99m-dmsa">Tc-99m DMSA</a>: renal imaging, parenchymal studies</li>-<li>-<a href="/articles/tc-99m-dtpa">Tc-99m DTPA</a>: renal imaging, glomerular filtration ratio</li>- +<a href="/articles/tc-99m-mag3">Tc-99m MAG3</a>: Tubular renal imaging agent. Measures ERPF</li>
-<a href="/articles/tc-99m-dtpa-aerosol">Tc-99m DTPA (aerosol)</a>: lung ventilation imaging, bronchial clearance</li>- +<a href="/articles/tc-99m-dmsa">Tc-99m DMSA</a>: Renal cortical imaging for assessment of acute pyelonephritis, cortical scarring, ectopic kidney </li>
-<a href="/articles/tc-99m-sestamibi">Tc-99m sestamibi</a>: parathyroid imaging</li>- +<a href="/articles/tc-99m-dtpa">Tc-99m DTPA</a>: Glomerular renal imaging agent, measures camera based glomerular filtration ratio (GFR) by Gates method. Another method is plasma sample method (cumbersome but reliable)</li>
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