Technetium-99m agents
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Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. A radiopharmaceutical labeled with 99mTc constitutes a coordination complex in which ligands bond to a central atom of 99mTc by coordinate covalent bonds.4
The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific radiopharmaceuticals and optimise the functional imaging of various structures:
- technetium-99m ECD: CNS imaging
- technetium-99m GHA : oncological imaging (e.g. low-grade glioma, lung)
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technetium-99m sulfur colloid
- splenic and hepatic imaging
- taken up by the spleen, Kupffer cells in the liver and a small proportion by bone marrow
- bone marrow and soft tissue infection scintigraphy
- lymphatic scintigraphy, e.g. sentinel node lymphoscintigraphy
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technetium-99m pertechnetate
- thyroid imaging
- Meckel scan
- testicular scintigraphy
- parathyroid subtraction study
- gastric emptying, intestinal and rectal functional studies
- technetium-99m MDP: bone scintigraphy
- technetium-99m MAA: lung perfusion imaging
- technetium-99m teboroxime: cardiac imaging
- technetium-99m metformin
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technetium-99m MIBI
- cardiac imaging
- parathyroid imaging
- technetium-99m HIDA : hepatobiliary scintigraphy
- technetium-99m HMPAO: cerebral perfusion imaging
- technetium-99m HMPAO labelled WBC: infection scintigraphy
- technetium-99m-labeled monoclonal antibody fragments: infection scintigraphy, approved for osteomyelitis
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technetium-99m labelled RBC
- assessment of occult gastrointestinal haemorrhage
- assessment of vascular lesions, e.g. hepatic haemangioma
- assessment of cardiac function, first pass or equilibrium
- technetium-99m labelled heat-denatured RBC: specific splenic assessment, gold-standard in splenosis
- technetium-99m MAG3: renal imaging
- technetium-99m DMSA: renal cortical imaging
- technetium-99m DTPA: glomerular renal imaging, glomerular filtration ratio
- technetium-99m DTPA (aerosol): lung ventilation imaging, bronchial clearance
- technetium-99m sestamibi: parathyroid imaging
-<p><strong>Technetium agents</strong> based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific <a href="/articles/radiopharmaceuticals">radiopharmaceuticals</a> and optimise the functional imaging of various structures:</p><ul>- +<p><strong>Technetium agents</strong> based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. A radiopharmaceutical labeled with <sup>99m</sup>Tc constitutes a coordination complex in which ligands bond to a central atom of <sup>99m</sup>Tc by coordinate covalent bonds.<sup>4 </sup></p><p>The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific <a href="/articles/radiopharmaceuticals">radiopharmaceuticals</a> and optimise the functional imaging of various structures:</p><ul>
-<a title="Technetium-99m diethylene-triamine-pentaacetate" href="/articles/tc-99m-dtpa">technetium-99m DTPA</a>: glomerular renal imaging, glomerular filtration ratio</li>- +<a href="/articles/tc-99m-dtpa">technetium-99m DTPA</a>: glomerular renal imaging, glomerular filtration ratio</li>
References changed:
- 4. M. P. Natale. P&C 5.1. Tecnico di radiologia. Guida completa alla preparazione di test preselettivi e prove pratiche per TSRM. Con software di simulazione. (2019) <a href="https://books.google.co.uk/books?vid=ISBN9788865846483">ISBN: 9788865846483</a><span class="ref_v4"></span>
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