Histiocytic sarcoma

Histiocytic sarcoma is a rare malignant haematopoietic neoplasm that has been reported in association with other hematological malignancies (particularly B and T cell lymphomas).

Pathology

It comprises of tumour cells derived from the monocyte/macrophage lineage.

Location

It usually occurs in lymph nodes, skin, and the gastrointestinal tract. Occurrence in the CNS system has also been rarely reported 3.

Prognosis

The overall prognosis is generally poor due to rapid progression and poor response to therapy.  Tumour size may be prognostic factor.

History and etymology

It was first described by Mathé et al in 1970.

See also

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Article Information

rID: 48058
System: Haematology
Synonyms or Alternate Spellings:
  • Histiocytic sarcomas
  • Histiocytic sarcoma (HS)

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