Histiocytic sarcoma

Histiocytic sarcoma is a rare malignant haematopoietic neoplasm that has been reported in association with other haematological malignancies (particularly B and T cell lymphomas).

It comprises of tumour cells derived from the monocyte/macrophage lineage.

It usually occurs in lymph nodes, skin, and the gastrointestinal tract. Occurrence in the CNS system has also been rarely reported 3.

The overall prognosis is generally poor due to rapid progression and poor response to therapy.  Tumour size may be a prognostic factor.

It was first described by Mathé et al. in 1970.

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Article information

rID: 48058
Synonyms or Alternate Spellings:
  • Histiocytic sarcomas
  • Histiocytic sarcoma (HS)

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