Dr Daniel J Bell and Dr Henry Knipe et al.

Hypersplenism is a cytopenia resulting from blood pooling in the spleen and is almost always associated with splenomegaly

There is an almost overwhelming list, some more common causes are given below 1,3,4:

Hypersplenism does not often require treatment because the cytopenia is often not severe enough to cause significant bleeding 1. Splenectomy or splenic embolisation can be considered if warranted. 

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Article information

rID: 35105
System: Haematology
Tag: spleen
Synonyms or Alternate Spellings:
  • Hypersplenia

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Cases and figures

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    Case 1: Splenomegaly with volvulus
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