Smooth muscle actin
Last revised by Patrick J Rock
on 28 Sep 2020
Citation, DOI, disclosures and article data
Citation:
Rock P, Sharma R, Gaillard F, Smooth muscle actin. Reference article, Radiopaedia.org (Accessed on 18 Jan 2025) https://doi.org/10.53347/rID-82175
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rID:
82175
Article created:
16 Sep 2020,
Patrick J Rock
Disclosures:
At the time the article was created Patrick J Rock had no recorded disclosures.
View Patrick J Rock's current disclosures
Last revised:
28 Sep 2020,
Patrick J Rock
Disclosures:
At the time the article was last revised Patrick J Rock had no recorded disclosures.
View Patrick J Rock's current disclosures
Revisions:
6 times, by
3 contributors -
see full revision history and disclosures
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Smooth muscle actin (SMA) is a target in immunohistochemistry which is positive in cell lines which expresses actin. It is generally used to identify cells of myoepithelial origin 1.
Related pathology
References
- 1. Rubisz, Piotr, Ciebiera, Michał, Hirnle, Lidia, Zgliczyńska, Magdalena, Łoziński, Tomasz, Dzięgiel, Piotr, Kobierzycki, Christopher. The Usefulness of Immunohistochemistry in the Differential Diagnosis of Lesions Originating from the Myometrium. (2019) International Journal of Molecular Sciences. 20 (5): 1136. doi:10.3390/ijms20051136 - Pubmed
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- cells (general)
- general cellular structure
- cell membrane
- nucleus
- nucleolus
- chromatin
- cytoplasm
- organelles
- cytoskeleton
- endoplasmic reticulum
- smooth
- rough
- Golgi complex
- lysosomes
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- ribosomes
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blood
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- granular
- non-granular
- central nervous system
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blood
- general cellular structure
- immunohistochemistry
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histological stains
- alcian blue stain
- azan stain
- Giemsa stain
- Gram stain
- hematoxylin and eosin stain (H&E)
- immunoperoxidase staining
- Luxol fast blue stain
- Masson's trichrome stain
- methylene blue
- Nissl stain
- oil red O stain
- osmium stain
- Papanicolaou stain
- periodic acid-Schiff reaction (PAS)
- Prussian blue stain
- reticulin stain
- silver stain
- Sudan stains
- toluidine blue stain
- van Gieson stain
- Ziehl-Neelsen stain
- specific features and structures