Technetium-99m agents

Last revised by Craig Hacking on 12 Sep 2024

Technetium agents based on the technetium-99m (Tc-99m) radioisotope are frequently used agents in medical imaging. A radiopharmaceutical labeled with Tc-99m constitutes a co-ordination complex in which ligands bond to a central atom of Tc-99m by co-ordinate covalent bonds 4 .

The radioactive technetium radiotracer can be chelated to a number of different compounds to create specific radiopharmaceuticals and optimize the functional imaging of various structures:

Cases and figures

  • Figure 1: Technetium-99m decay
  • 99m Tc pertechnatate: ectopic thyroid
  • 99m Tc MDP: bone uptake
  • Normal dynamic renal scintigraphy
  • 99m Tc MAG3 scan showing PUJ obstruction
  • 99m Tc ECD brain perfusion scan
  • Chyle leak with Tc-99m colloid
  • Tc 99m pertechnetate: Meckel
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