De Quervain tenosynovitis, also known as washerwoman's sprain/strain, is a painful stenosing tenosynovitis involving the first extensor (dorsal) tendon compartment of the wrist (typically at the radial styloid). This compartment contains the abductor pollicis longus (APL) and extensor pollicis brevis (EPB) tendons.
De Quervain tenosynovitis is the second most common entrapment tendinopathy in the hand following trigger finger. It usually occurs in middle-aged individuals and is around 3x more common in women (~80% of cases). Most cases are associated with overuse, however, local trauma can also precipitate the condition. Mothers and childcare workers are particularly afflicted due to lifting of infants, while secretarial and nursing workers are also over-represented 6.
Patients present with pain on thumb and wrist movement and with focal tenderness and swelling over the radial styloid. There is usually a positive Finkelstein test (pain on passive ulnar deviation) although this is not pathognomonic. Triggering or crepitus may also be elicited 3.
The APL and EPB tendons are tightly secured against the radial styloid by the overlying extensor retinaculum which creates a fibro-osseous tunnel. Thickening of the retinaculum and tendons from acute or repetitive trauma restrains normal gliding within the sheath. This causes inflammation and further oedematous thickening of the tendon exacerbating the local stenosing effect. Microscopically there are inflammatory cells found within the tendon sheath 3.
In ~10% of patients, there is an intertendinous septum between APL and EPB. The absence of a septum is associated with very high rates (almost 100%) of complete symptom resolution with conservative management. Presence of a septum increases the likelihood that surgical management will be required.
Plain radiographs are non-diagnostic of the condition but may show non-specific signs and can help exclude other causes of pain such as fracture, carpometacarpal arthritis and osteomyelitis. Signs include:
- soft-tissue swelling over the radial styloid
- focal abnormalities of the radial styloid including cortical erosion, sclerosis or periosteal reaction 6
Ultrasound is very often diagnostic. Findings include 5:
- oedematous tendon thickening of APL and EPB at the level of the radial styloid (compare with the contralateral side)
- increased fluid within the first extensor tendon compartment tendon sheath
- thickening of overlying retinaculum and the synovial sheath
- peritendinous subcutaneous oedema resulting in a hypoechoic halo sign
- peritendinous subcutaneous hyperaemia on Doppler imaging
It is important to assess for an intertendinous septum which can usually be identified if present. Ultrasound is often used to guide corticosteroid injections into the tendon compartment to treat the condition.
MRI is very sensitive and specific and useful for detecting mild disease where ultrasound may be equivocal. Presence or absence of intertendinous septum can be assessed. Findings include 3:
- increased fluid within tendon sheath (high T2, low-intermediate T1)
- debris within sheath (intermediate T1 signal)
- thickened oedematous retinaculum
- peritendinous subcutaneous oedema
- peritendinous subcutaneous contrast enhancement
- tendon enlargement maximal at radial styloid and often greater at the medial aspect of the tendon
- slightly increased intratendinous T1 and T2 signal compared to other tendons
- striated appearance of tendons due to multiple enlarged slips
- longitudinal tendon tear
- linear high T2 signal due to fluid within the split
- more common in APL
Treatment and prognosis
Conservative treatment with anti-inflammatory medications, rest and splinting can be effective. Corticosteroid injection into the tendon sheath is usually very effective with 50% of patients experiencing symptom resolution after one injection. A second injection given at least a month later permanently relieves symptoms in another 40-45% of patients 4.
Rarely is surgical decompression required even when there is an intertendinous septum although this does increase the likelihood. Long-term complications are rare but can include perineural fibrosis of the superficial radial nerve and tendon instability after surgery 3.
History and etymology
The condition was first described by Fritz de Quervain (Swiss surgeon) in 1895 2. He is responsible for introducing iodinised table salt in order to help prevent goitre.
On imaging consider:
- 1. Anderson SE, Steinbach LS, De Monaco D et-al. "Baby wrist": MRI of an overuse syndrome in mothers. AJR Am J Roentgenol. 2004;182 (3): 719-24. AJR Am J Roentgenol (full text) - Pubmed citation
- 2. DeQuervain F. Ueber eine Form von chronischer Tendovaginitis. Corresp Blatt Schweizer Arzte. 1895;25:389-94.
- 3. Stoller DW, Tirman PF, Bredella MA. Diagnostic imaging, Orthopaedics. Amirsys Inc. (2004) ISBN:0721629202. Read it at Google Books - Find it at Amazon
- 4. Sawaizumi T, Nanno M, Ito H. De Quervain's disease: efficacy of intra-sheath triamcinolone injection. Int Orthop. 2007;31 (2): 265-8. doi:10.1007/s00264-006-0165-0 - Free text at pubmed - Pubmed citation
- 5. Diop AN, Ba-Diop S, Sane JC et-al. [Role of US in the management of de Quervain's tenosynovitis: review of 22 cases] J Radiol. 2008;89 (9 Pt 1): 1081-4. J Radiol (link) - Pubmed citation
- 6. Chien AJ, Jacobson JA, Martel W et-al. Focal radial styloid abnormality as a manifestation of de Quervain tenosynovitis. AJR Am J Roentgenol. 2001;177 (6): 1383-6. AJR Am J Roentgenol (full text) - Pubmed citation