Hypertrophic osteoarthropathy
Updates to Synonym Attributes
Updates to Synonym Attributes
Updates to Article Attributes
Hypertrophic osteoarthropathy is characterised by a proliferative periostitis involving the long bones seen most commonly in patients with lung, liver, an GI disorders. When associated with a lung condition it is also termed hypertrophic pulmonary osteoarthropaty (HPOA) and when associated with cancer is considered a paraneoplastic syndrome.
Clinical presentation
It is usually painful and associated with clubbing of the fingers or toes. The
Pathology
The causes of hypertrophic osteoarthropathy include:
- lung
- bronchogenic carcinoma: non small cell lung cancer is the strongest malignant association
- pulmonary lymphoma
- lung abscess
- bronchiectasis
-
pulmonary metastases
(esp.(especially from osteosarcoma) - pleural fibroma
- mesothelioma
- cyanotic congenital heart disease
- gastrointestinal tract and liver
- familial
- idiopathic
Radiographic features
Plain film
Typically seen as a long metaphyseal and diaphyseal smooth periosteal reaction involving the long bones.
With disease progression, periostitis becomes more prominent or multilayered, and extends to the epiphyses 1.
Differential diagnosis
Consider the differential for a smooth periosteal reaction.
-<p><strong>Hypertrophic osteoarthropathy</strong> is characterised by a proliferative periostitis involving the long bones seen most commonly in patients with lung, liver, an GI disorders. When associated with a lung condition it is also termed <strong>hypertrophic pulmonary osteoarthropaty (HPOA)</strong>. It is usually painful and associated with clubbing of the fingers or toes. The causes of <strong>hypertrophic osteoarthropathy</strong> include:</p><ul>- +<p><strong>Hypertrophic osteoarthropathy</strong> is characterised by a proliferative periostitis involving the long bones seen most commonly in patients with lung, liver, an GI disorders. When associated with a lung condition it is also termed <strong>hypertrophic pulmonary osteoarthropaty (HPOA)</strong> and when associated with cancer is considered a <a title="Paraneoplastic syndrome" href="/articles/paraneoplastic-syndromes">paraneoplastic syndrome</a>. </p><h4>Clinical presentation</h4><p>It is usually painful and associated with clubbing of the fingers or toes. </p><h4>Pathology</h4><p>The causes of <strong>hypertrophic osteoarthropathy</strong> include:</p><ul>
-<a href="/articles/pulmonary-metastases">pulmonary metastases</a> (esp. from <a href="/articles/osteosarcoma">osteosarcoma</a>)</li>- +<a href="/articles/pulmonary-metastases">pulmonary metastases</a> (especially from <a href="/articles/osteosarcoma">osteosarcoma</a>)</li>
References changed:
- 3. Felix S. Chew. Skeletal Radiology. (2010) ISBN: 9781608317066 - <a href="http://books.google.com/books?vid=ISBN9781608317066">Google Books</a>
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