Parotid gland enlargement
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Parotid enlargement (also known as parotidomegaly) has a wide differential given the significant breadth of pathology that can affect the parotid gland. These can be separated by the standard surgical sieve approach into infective, inflammatory, immune, neoplastic, infiltrative, and congenital causes.
Differential diagnosis
Infection
- cat-scratch fever
- HIV parotitis
- mumps
- parotid abscess secondary to acute bacterial sialadenitis (acute parotitis)
- syphilis
- tuberculosis
Inflammatory
- benign lymphoepithelial lesions
- chronic recurrent sialadenitis
- sarcoidosis
Immune-mediated
- Mikulicz syndrome
- Sjogren syndrome (myoepithelial sialadenitis)
Miscellaneous
- pneumoparotid
- sialolithiasis
- sialosis
- bulimia nervosa
Neoplastic
See also: salivary gland tumours
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benign
- angiolipoma
- benign lymphoepithelial lesions (may be multiple and bilateral)
- facial nerve neurofibroma
- parotid haemangioma
- parotid lipoma
- parotid oncocytoma
- pleomorphic adenoma
- Warthin tumour (commonest bilateral tumour)
- malignant primary tumour
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metastatic
- squamous cell carcinoma
- malignant melanoma of periauricular region
- thyroid carcinoma
-
lymphoproliferative
- leukaemia
- lymphoma
- primary NHL (MALToma)
Congenital
-<li><a title="acinic cell carcinoma" href="/articles/acinic-cell-carcinoma-salivary-glands">acinic cell carcinoma</a></li>- +<li><a href="/articles/acinic-cell-carcinoma-salivary-glands">acinic cell carcinoma</a></li>
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Image 1 CT (C+ arterial phase) ( update )
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Case 21: parotid lipoma
Image 2 CT (C+ arterial phase) ( update )
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Case 42: parotid lymphoepithelial cyst
Image 3 CT (non-contrast) ( update )
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Case 53: parotid lipoma
Image 4 CT (C+ arterial phase) ( update )
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Case 64: acute parotitis
Image 5 CT (C+ arterial phase) ( update )
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Case 75: parotid gland lymphoma - bilateral
Image 6 CT (C+ delayed) ( update )
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Case 86: parotid gland abscess
Image 7 CT (C+ portal venous phase) ( update )
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Case 97: acute parotitis
Image 8 CT (C+ delayed) ( update )
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Case 108: sarcoidosis