Dysphagia refers to subjective awareness of difficulty or obstruction during swallowing. It is a relatively common and increasingly prevalent clinical problem.
Fluoroscopy is the mainstay of imaging assessment but manometry can help evaluate the esophageal motor pattern and lower esophageal sphincter function 1.
Dysphagia is common in older age groups. Women are more prone to have dysphagia than men (80% versus 20%) 2.
Dysphagia may be classified depending on the location of this sensation as oropharyngeal or substernal.
Oropharyngeal dysphagia occurs when a patient symptomatically localizes a sensation of blockage in the throat.
- laryngeal penetration (when contrast seen entering the larynx at fluoroscopy) or aspiration (when contrast extends inferiorly through the true vocal), which are common with patients who have a history of neurologic disorders including stroke
- cricopharyngeal muscle spasm
- oesophageal web
- oesophageal diverticula, e.g. Zenker, Killian-Jamieson, and epiphrenic diverticula
- extrinsic compression, e.g.
- multinodular goitre
- anterior osteophytes from cervical spine disease
- occasionally as a complication of anterior cervical spine fusion (~4%) 6
- diffuse oesophageal spasm (DES): characterized by multiple spontaneous and uncoordinated esophageal contractions which have the classic "corkscrew" appearance at oesophagogram
- achalasia: characterized by esophageal dilatation with distal tapered beaklike narrowing at the gastro-oesophageal junction
- scleroderma: characterized by esophageal dilatation with a patulous gastroesophageal junction
- oesophageal stricture
- peptic strictures most often typically appear as smooth, tapered narrowing in the distal esophagus
- Barrett oesophagus occurs often as a consequence of GERD in the mid-to-upper esophagus
- ring stricture: Schatzki ring is the most common type of esophageal ring, associated with hiatus hernias
- other less common causes of benign strictures include corrosive oesophagitis, Crohn disease, Behçet disease, and eosinophilic esophagitis
- extrinsic mass such as lung cancer or vascular compression, e.g. aberrant right subclavian artery (i.e. dysphagia lusoria)
- esophageal infections, such as candidiasis, herpes virus, human immunodeficiency virus (HIV), and cytomegalovirus (CMV)
- oesophageal carcinoma can appear infiltrative, ulcerative, polypoid, and/or varicoid at oesophagography
- impacted foreign body or food bolus in the esophagus; water-soluble contrast should be used for increased risk of perforation
- modified barium swallow: used for the evaluation of swallowing mechanisms specifically for aspiration or penetration, this exam is usually performed in conjunction with a speech therapist to assess swallowing function and response to therapeutic strategies 4
- barium swallow / esophagography: provides anatomic and functional information about the pharynx, oesophagus, gastro-oesophageal junction, and gastric cardia, including evaluation of esophageal motility and assessment for gastroesophageal reflux
barium tablet: may be used to detect subtle areas of esophageal narrowing 5
- the tablet (of known 12.5mm diameter) should be swallowed with a small amount of water and passage is observed at fluoroscopy; f the tablet becomes lodged in a particular location the patient should swallow a small amount of additional water and if the tablet remains lodged, a more detailed assessment should be performed
Cross-sectional imaging may be used especially if there is a mass effect on the oesophagus seen at oesophagography or for evaluation of oesophageal tumors.
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- 3. Kuo P, Holloway RH, Nguyen NQ. Current and future techniques in the evaluation of dysphagia. J. Gastroenterol. Hepatol. 2012;27 (5): 873-81. doi:10.1111/j.1440-1746.2012.07097.x - Pubmed citation
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- 6. Carucci LR, Turner MA, Yeatman CF. Dysphagia secondary to anterior cervical fusion: radiologic evaluation and findings in 74 patients. AJR Am J Roentgenol. 2015;204 (4): 768-75. doi:10.2214/AJR.14.13148 - Pubmed citation