Uterine lymphoma

Last revised by Dr Jeremy Jones on 18 Feb 2018

Uterine lymphoma refers to involvement of the uterus with lymphoma. Some authors also place lymphoma of the uterine cervix under this group.

It is rare condition with initial uterine involvement occurring in only 1% of patients with lymphoma 3. However, uterine involvement is more common as part of a generalized process, as shown in 40-50% of these patients at autopsy. 

Uterine lymphoma usually occurs as secondary involvement of the uterus with established extra uterine involvement elsewhere. Primary uterine involvement is much rarer.

In general imaging features of lymphoma involving the uterus are considered non-specific although some features may suggest towards the diagnosis.

Reported characteristic MR imaging findings include:

  • diffuse enlargement of the uterus may be present 4
  • homogeneous intermediate signal intensity of an indistinct mass on T1- and T2-weighted images 1
  • T1: involved regions slightly hypointense to rest of uterus 5
  • T2: involved regions slightly hyperintense to rest of uterus 5
  • normally there is preservation of the endometrial lining (with an intact junctional zone 4) and uterine architecture 1,8 although some studies report disruption of zonal architecture 7

ADVERTISEMENT: Supporters see fewer/no ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.