Primary cardiac lymphoma is a rare occurrence, representing only 10% of primary malignant cardiac tumours (1% of all primary cardiac tumours).
Secondary involvement of the heart by disseminated lymphoma (diffuse large B-cell) is more common than primary cardiac lymphoma, but is still a rare occurrence.
Both forms are much more common in patients with HIV/AIDS.
Cardiac lymphoma may present with dyspnoea, oedema, or arrhythmia. Pericardial effusion may give rise to tamponade.
- may detect an intracavitary mass or pericardial effusion
- multiple circumscribed polypoid masses or an ill-defined infiltrative lesion
- more common in right atrium
- frequently associated with pericardial effusion
- less likely to show necrosis than a cardiac sarcoma
- heterogeneous contrast enhancement, isoattenuating or hypoattenuating relative to myocardium
- atrial, particularly right atrial predominant location
- variable signal intensity and contrast enhancement
Treatment and prognosis
Prognosis is poor with a median survival of 7 months after diagnosis.
- 1. Fuster V, Walsh R, Harrington R. Hurst's the heart. McGraw-Hill Professional. ISBN:0071636463. Read it at Google Books - Find it at Amazon
- 2. Ceresoli GL, Ferreri AJ, Bucci E et-al. Primary cardiac lymphoma in immunocompetent patients: diagnostic and therapeutic management. Cancer. 1997;80 (8): 1497-506. Pubmed citation
- 3. Versluis PJ, Lamers RJ, van Belle AF. Primary malignant lymphoma of the heart: CT and MRI features. Rofo. 1995;162 (06): 533-4. doi:10.1055/s-2007-1015932 - Pubmed citation
- 4. Tada H, Asazuma K, Ohya E et-al. Images in cardiovascular medicine. Primary cardiac B-cell lymphoma. Circulation. 1998;97 (2): 220-1. Pubmed citation
- 5. Dorsay TA, Ho VB, Rovira MJ et-al. Primary cardiac lymphoma: CT and MR findings. J Comput Assist Tomogr. 1993;17 (6): 978-81. Pubmed citation
- 6. Miguel CE, Bestetti RB. Primary cardiac lymphoma. Int. J. Cardiol. 2011;149 (3): 358-63. doi:10.1016/j.ijcard.2010.02.016 - Pubmed citation
- 7. Jeudy J, Kirsch J, Tavora F et-al. From the radiologic pathology archives: cardiac lymphoma: radiologic-pathologic correlation. Radiographics. 2012;32 (5): 1369-80. doi:10.1148/rg.325115126 - Pubmed citation
- overview of lymphoma
WHO classification of tumours of haematopoietic and lymphoid tissues
- Hodgkin lymphoma
- mature B-cell lymphoma
- mature T-cell and NK-cell lymphoma
- post-transplant lymphoproliferative/lymphoproliferation disorders
- location-specific lymphomas
- central nervous system
- head and neck lymphoma
- thoracic lymphoma
- gastrointestinal lymphoma
- hepatobiliary lymphoma
- genitourinary lymphoma
- musculoskeletal lymphoma
- cutaneous lymphoma
- lymphoma staging