Cardiac lymphoma

Dr Owen Kang and Dr Matt A. Morgan et al.

Cardiac lymphoma is a rare tumour of the myocardium and/or pericardium. It may be considered as primary or secondary.

Primary cardiac lymphoma is a rare occurrence, representing only 10% of primary malignant cardiac tumours (1% of all primary cardiac tumours).

Secondary involvement of the heart by disseminated lymphoma (diffuse large B-cell) is more common than primary cardiac lymphoma, but is still a rare occurrence.

Both forms are much more common in patients with HIV/AIDS.

Cardiac lymphoma may present with dyspnoea, oedema, or arrhythmia. Pericardial effusion may give rise to tamponade.

Echocardiography
Cardiac CT
  • multiple circumscribed polypoid masses or an ill-defined infiltrative lesion
  • more common in right atrium
  • frequently associated with pericardial effusion
  • less likely to show necrosis than a cardiac sarcoma
  • heterogeneous contrast enhancement, isoattenuating or hypoattenuating relative to myocardium
Cardiac MRI
  • atrial, particularly right atrial predominant location
  • variable signal intensity and contrast enhancement

Prognosis is poor with a median survival of 7 months after diagnosis.


Lymphoma
Share article

Article Information

rID: 32090
System: Cardiac
Section: Pathology
Synonyms or Alternate Spellings:
  • Pericardial lymphoma
  • Myocardial lymphoma

Support Radiopaedia and see fewer ads

Cases and Figures

  • Drag
    Case 1: secondary
    Drag here to reorder.
  • Updating… Please wait.
    Loadinganimation

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.