Medial medullary syndrome

Medial medullary syndrome, also known as jerine syndrome,  is secondary to  thrombotic or embolic occlusion of small perforating branches from vertebral or proximal basilar artery supplying the medial aspect of medulla oblongata1,2.

Represents less than 1% of brainstem stroke syndromes 1,2.

It is characterized by contralateral hemiplegia/hemiparesis as well as hemisensory loss with ipsilateral hypoglossal palsy (ipsilateral tongue weakness and atrophy) from involvement of CN XII nucleus 1,2. Other manifestations such as vertigo, nausea, or contralateral limb ataxia are also reported 1,2.

The syndrome was first described by Joseph Jules Déjerine (1849-1917), a French neurologist, in 1915 3.

Stroke and intracranial haemorrhage

Article information

rID: 32266
Section: Syndromes
Synonyms or Alternate Spellings:
  • Dejerine syndrome
  • Dejerine's syndrome
  • Déjerine syndrome
  • Déjerine's syndrome

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Cases and figures

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