Extra skeletal myxoid chondrosarcomas typically occur in the extremities, with the thigh being most common. They occur at all ages but typically around the age of 50 3.
Extra skeletal mesenchymal chondrosarcomas on the other hand tend to occur in young adults. They are seen also in the thigh, but also have a predilection for the head and neck, occurring in the meninges, the orbit and even in the brain.
Chondrosarcomas have been reported in most other parts of the body, although with less frequency, including:
- meninges of the brain and spinal cord (most common)
- lower limb (particularly thigh)
- soft tissues of the head and neck
- sinonasal cavity 4
- solid organs
- pancreas 2
Their appearance is the same as that of chondrosarcomas elsewhere (see generic chondrosarcoma article for radiographic features).
- 1. Shapeero LG, Vanel D, Couanet D et-al. Extraskeletal mesenchymal chondrosarcoma. Radiology. 1993;186 (3): 819-26. Pubmed citation
- 2. Oh B, Han Y, Lee B et-al. Korean Journal of Radiology. 2007;8 (6): . doi:10.3348/kjr.2007.8.6.541
- 3. Murphey MD, Walker EA, Wilson AJ et-al. From the archives of the AFIP: imaging of primary chondrosarcoma: radiologic-pathologic correlation. Radiographics. 2003;23 (5): 1245-78. doi:10.1148/rg.235035134 - Pubmed citation
- 4. Kim Y, Im S, Lim G et-al. Korean Journal of Radiology. 2007;8 (5): . doi:10.3348/kjr.2007.8.5.452
The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the paediatric patient.
- bone-forming tumours
- cartilage-forming tumours
- chondromyxoid fibroma
- fibrous bone lesions
- bone marrow tumours
- other bone tumours or tumour-like lesions
- aneurysmal bone cyst
- benign fibrous histiocytoma
- giant cell tumour of bone
- Gorham massive osteolysis
- haemophilic pseudotumour
- intradiploic epidermoid cyst
- intraosseous lipoma
- musculoskeletal angiosarcoma
- musculoskeletal haemangiopericytoma
- primary intraosseous haemangioma
- simple bone cyst
- impending fracture risk