Extraskeletal chondrosarcoma

Extraskeletal chondrosarcomas make up only 2% of soft-tissue sarcomas  and only 1% of all chondrosarcomas.

They tend to be of higher grade than run-of-the-mill conventional intramedullary chondrosarcomas, with the majority being of the myxoid (most common) or mesenchymal varieties 3

Location

Extra skeletal myxoid chondrosarcomas typically occur in the extremities, with the thigh being most common. They occur at all ages but typically around the age of 50 3.

Extra skeletal mesenchymal chondrosarcomas on the other hand tend to occur in young adults. They are seen also in the thigh, but also have a predilection for the head and neck, occurring in the meninges, the orbit and even in the brain.

Chondrosarcomas have been reported in most other parts of the body, although with less frequency, including:

  • meninges of the brain and spinal cord (most common)
  • lower limb (particularly thigh)
  • soft tissues of the head and neck
    • orbit
    • larynx
    • sinonasal cavity 4
  • solid organs
    • pancreas 2

Their appearance is the same as that of chondrosarcomas elsewhere (see generic chondrosarcoma article for radiographic features). 


Bone tumours

The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the paediatric patient.

Share Article

Article Information

rID: 6531
Synonyms or Alternate Spellings:
  • Extraskeletal chondrosarcoma
  • Extra skeletal chondrosarcomas

Support Radiopaedia and see fewer ads

  • Drag
    Coronal
    Case 1: laryngeal chondrosarcoma
    Drag here to reorder.
  • Drag
    Case 2
    Drag here to reorder.
  • Updating… Please wait.
    Loadinganimation

    Alert accept

    Error Unable to process the form. Check for errors and try again.

    Alert accept Thank you for updating your details.