Intradiploic epidermoid cyst
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Intradiploic epidermoid cysts refer to epidermoid cysts that occur in the diploë of the skull.
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Painless slowly progressive scalp swelling.
epidermoid cysts may be congenital (most common, arising from ectodermal inclusion during neural tube closure and subsequently remain within the cranial bones) or acquired (e.g. post-surgical or post-traumatic implantation) 4
intradiploic epidermoids are less frequent than the intradural variety 1
Intradiploic epidermoids occurs within the frontal, parietal, occipital and sphenoid bones, as well as the spine 1.
rounded or lobulated area of bone destruction, well-delineated sclerotic scalloped margins
non-enhancing hypodense lesion with sharply demarcated bony defects and zones of calcifications
it may alter the outer and/or inner tables of the skull (the inner table more than the outer)
T1: slightly hyperintense to the CSF
T2: isointense/hyperintense to the CSF
FLAIR: hyperintense to the CSF space
DWI: restricted diffusion with characteristic hyperintensity
History and etymology
The first intradiploic epidermoid cyst was reported by J Müller in 1838 5.
The radiological pattern of intradiploic epidermoids was first described by Cushing in 1922.
- 1. Osborn AG, Salzman KL, Barkovich AJ. Diagnostic Imaging. Lippincott Williams & Wilkins. (2009) ISBN:1931884722. Read it at Google Books - Find it at Amazon
- 2. Krupp W, Heckert A, Holland H et-al. Giant intradiploic epidermoid cyst with large osteolytic lesions of the skull: a case report. J Med Case Rep. 2012;6 (1): 85. doi:10.1186/1752-1947-6-85 - Free text at pubmed - Pubmed citation
- 3. www.ajns.paans.org. Forbidden. Read relevant article. Accessed on 19/01/2016
- 4. Osborn AG, Preece MT. Intracranial cysts: radiologic-pathologic correlation and imaging approach. Radiology. 2006;239 (3): 650-64. doi:10.1148/radiol.2393050823 - Pubmed citation
- 5. Müller J. Über den feineren Bau und die Formen der krankhaftenGeschwfilste. Berlin, Germany: G. Reimer; 1838.