Citation, DOI & article data
Spinocerebellar ataxias comprise a large (and expanding) group of diseases characterized by degeneration of the spinal cord and cerebellum.
There are well over 25 individual spinocerebellar ataxias referred to sequentially as SCA1, SCA2, ... in order of their discovery and genetic characterization.
Although individual spinocerebellar ataxias vary in morphological changes, atrophy of the cerebellum is a relatively constant finding. Extracerebellar regions are also affected, depending on the specific SCA 1.