A ferruginous body is a histological finding in interstitial lung disease that is a result inorganic dust inhalation.
Macrophage ingestion of the inorganic fibre results in a fibrotic reaction with encasement of the fibre in iron-rich material that is derived from proteins such as ferritin and haemosiderin.
Where asbestos is confirmed as the fibre in the nidus of the body, it is termed an asbestos body.
- 1. Churg AM, Warnock ML. Asbestos and other ferruginous bodies: their formation and clinical significance. Am. J. Pathol. 1981;102 (3): 447-56. - Free text at pubmed - Pubmed citation