Pulmonary lymphoma refers to lung parenchymal involvement with lymphoma.
On this page:
Article:
Images:
Images:
Pathology
It can be broadly divided as primary or secondary:
-
primary pulmonary lymphoma: (rare) usually non-Hodgkin lymphoma which is limited to the lung with or without mediastinal lymph node involvement and with no evidence of extrathoracic dissemination for at least 3 months after the initial diagnosis
- low-grade B-cell lymphoma (MALToma) - commonest ~ 80% of primary pulmonary lymphoma
- high-grade B-cell lymphoma - most commonly B-cell, occasionally anaplastic and peripheral T-cell types
- primary pulmonary plasmacytoma (rare)
- pulmonary intravascular lymphoma (rare)
- angiocentric immunoproliferative lesion (lymphomatoid granulomatosis)
- secondary pulmonary lymphoma: relatively common
Two additional categories have also been described which include 4:
- lymphoma in patients with post-transplant lymphoproliferative disorders (PTLD)
- AIDS-related pulmonary lymphoma (ARL/ARPL)
Radiographic features
CT
A number of features may be present on HRCT which include:
- a mass or mass-like consolidation greater than 1 cm with or without cavitations or bronchograms - most common finding according to one study 2
- masses of pleural origin
- nodules <1 cm
- alveolar or interstitial infiltrates
- peribronchial or perivascular thickening with or without atelectasis
- pleural effusions
- hilar or mediastinal lymphadenopathy
See also
- pulmonary pseudolymphoma: benign inflammatory lymphocytic infiltrate of the lungs
- pulmonary lymphoproliferative diseases