Hepatic carcinosarcoma
Citation, DOI, disclosures and article data
Citation:
Knipe H, Jones J, Bell D, et al. Hepatic carcinosarcoma. Reference article, Radiopaedia.org (Accessed on 17 Jan 2025) https://doi.org/10.53347/rID-49400
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rID:
49400
Article created:
Disclosures:
At the time the article was created Henry Knipe had no recorded disclosures.
View Henry Knipe's current disclosures
Last revised:
Disclosures:
At the time the article was last revised Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosures
Revisions:
5 times, by
4 contributors -
see full revision history and disclosures
Systems:
Tags:
Synonyms:
- Liver carcinocarcinoma
- Hepatic malignant mixed tumour
- Hepatic spindle cell carcinoma
- Hepatic pseudosarcoma
- Sarcomatoid carcinoma
- Hepatic carcinosarcomas
- Carcinosarcoma of liver
Hepatic carcinosarcoma is a very rare tumor that is defined by mixed histological features.
Terminology
This tumor has also been referred to as malignant mixed tumor, spindle cell carcinoma, pseudosarcoma or sarcomatoid carcinoma 1,2.
Pathology
Hepatic carcinocarcinoma contain a mixture of carcinomatous (usually hepatocellular or cholangiocellular) and sarcomatous elements 1,2.
Treatment and prognosis
This tumor has a very poor prognosis with high rates of metastatic disease 1.
References
- 1. Lao XM, Chen DY, Zhang YQ, Xiang J, Guo RP, Lin XJ, Li JQ. Primary carcinosarcoma of the liver: clinicopathologic features of 5 cases and a review of the literature. The American journal of surgical pathology. 31 (6): 817-26. doi:10.1097/01.pas.0000213431.07116.e0 - Pubmed
- 2. Kwon JH, Kang YN, Kang KJ. Carcinosarcoma of the liver: a case report. Korean journal of radiology. 8 (4): 343-7. doi:10.3348/kjr.2007.8.4.343 - Pubmed
- 3. Luchini C, Capelli P, Fassan M, Simbolo M, Mafficini A, Pedica F, Ruzzenente A, Guglielmi A, Corbo V, Scarpa A. Next-generation histopathologic diagnosis: a lesson from a hepatic carcinosarcoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 32 (17): e63-6. doi:10.1200/JCO.2012.47.5855 - Pubmed
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