Gallbladder cholecystosis

Last revised by Dr Jeremy Jones on 19 Sep 2021

Gallbladder cholecystoses are conditions characterized by the accumulation of cholesterol (and other fats) in the gallbladder. There are two main forms:

  • adenomyomatosis: mucosal hyperplasia with growth toward the muscular layer - thickened muscular layer. Cholesterol accumulation is intraluminal (within the Rokitansky-Aschoff sinuses), therefore, lined by mucosal epithelium 2,3
  • cholesterolosis: mucosal hyperplasia with the accumulation of cholesterol esters and triglycerides in the macrophages of the lamina propria - appearance is known as “strawberry gallbladder2,3

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