Target sign (neurofibromas)

The target sign of neurofibromas is seen on MRI and represents a T2 hyperintense rim surrounding a central area of low signal. It is believed to be due to a dense central area of collagenous stroma.

Although this sign is highly suggestive of a neurofibroma, it is occasionally also seen in schwannomas and malignant peripheral nerve sheath tumors 1-2.

Inspired signs
Share article

Article information

rID: 28498
Synonyms or Alternate Spellings:
  • Target sign of neurofibromata
  • Target sign of a neurofibroma
  • Target sign of neurofibromas

Support Radiopaedia and see fewer ads

Cases and figures

  • Case 1
    Drag here to reorder.
  • Case 2: peripheral nerve sheath tumor of the sciatic nerve
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.