Mucinous cystadenocarcinoma of the pancreas

Mucinous cystadenocarcinomas of the pancreas are a type of pancreatic mucinous tumour. It is considered the more malignant counterpart of a mucinous cystadenoma of the pancreas.

Like the more benign mucinous cystadenomas, these are found almost exclusively in females 4.

It is typically seen as a cystic pancreatic lesion with cysts that are less numerous and larger in size (with an average diameter of ~10-12 cm) than typically observed with serous cystadenomas/cystadenocarcinomas. Its external surface is often smooth, and it is composed of unilocular or multilocular large (>2-4 cm) cysts with a thicker wall 5.

On CT, they tend to appear as round to ovoid, externally smooth, near-water-density cystic lesions. Amorphous calcifications, septations and solid excrescences may be seen. Both mucinous cystadenomas and cystadenocarcinomas do not have central scars.

Signal characteristics of the cyst(s) can vary dependant on content. Mucin components exhibit high signal on T1 while calcific components are low signal on both T1 and T2 10. Pure cystic components show low signal on T1 and high signal on T2.

While surgical resection is the standard mode of treatment, even the overtly malignant mucinous cystadenocarcinomas carry a far better prognosis than solid ductal adenocarcinomas 1.

On ultrasound or CT consider

Pancreatic pathology
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Article information

rID: 17771
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Mucinous cystadenocarcinoma of pancreas
  • Pancreatic mucinous cystadenocarcinoma
  • Mucinous cystadenocarcinomas of pancreas
  • Pancreatic mucinous cystadenocarcinomas
  • Mucinous cystadenocarcinoma (pancreas)

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