Coca-Cola bottle sign (thyroid eye disease)

Last revised by Ian Bickle ◉ on 26 Dec 2020

Citation, DOI, disclosures and article data

Citation:

Bickle I, Elhusseiny A, Bell D, et al. Coca-Cola bottle sign (thyroid eye disease). Reference article, Radiopaedia.org (Accessed on 22 Sep 2023) https://doi.org/10.53347/rID-23936

DOI:

https://doi.org/10.53347/rID-23936

Permalink:

https://radiopaedia.org/articles/23936

rID:

23936

Article created:

19 Jul 2013, Ian Bickle ◉

Disclosures:

At the time the article was created Ian Bickle had no recorded disclosures.

View Ian Bickle's current disclosures

Last revised:

26 Dec 2020, Ian Bickle ◉

Disclosures:

At the time the article was last revised Ian Bickle had no recorded disclosures.

View Ian Bickle's current disclosures

Revisions:

16 times, by 7 contributors - see full revision history and disclosures

Systems:

Head & Neck

Sections:

Signs

Tags:

thyroid eye disease, endocrine

Synonyms:

Coke sign
Coke bottle deformity
Coke deformity

The Coca-Cola bottle sign refers to the appearance of the muscles of the orbit in thyroid eye disease. The belly of the muscle enlarges with sparing of the tendinous insertion, giving the appearance of the traditional Coca-Cola bottle.

The enlargement of the muscles follows the I'M SLOW format.

The nature of the enlargement is important as it is one of the chief findings to differentiate it from orbital pseudotumor, in which the tendinous insertion is also involved and enlarged, unlike in thyroid eye disease.