Ears of the lynx sign (brain)

The ear of the lynx sign refers to abnormal T2/FLAIR cone-shaped hyperintensity at the tip of the frontal horn of the lateral ventricles in the region of forceps minor which resembles the tufts of hair crowning the ears of a lynx. This sign is seen in hereditary spastic paraplegia associated with mutations of the spastic paraparesis gene 11 (SPG11) on chromosome 15 1,2. It is a characteristic early imaging finding of hereditary spastic paraplegia with thin corpus callosum (HSP-TCC). This sign has also been described in Marchiafava-Bignami disease 3.

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Article information

rID: 65663
Section: Signs
Synonyms or Alternate Spellings:

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