11-13 week antenatal scan
Citation, DOI, disclosures and article data
At the time the article was created Ayush Goel had no recorded disclosures.
View Ayush Goel's current disclosuresAt the time the article was last revised David Ndegwa had no financial relationships to ineligible companies to disclose.
View David Ndegwa's current disclosures- NT scan
- 11-14 week scan
- NB NT scan
- 11-13.6 week scan
- Nuchal translucency scan
- 12 week scan
- 11-13 week scan
11-13 week antenatal (nuchal translucency) scan is considered a routine investigation advised for fetal well-being as well as for early screening in pregnancy (see antenatal screening).
It includes multiple components and is highly dependent on the operator. Traditionally three factors are used to calculate the risk of trisomies:
-
must be 45 to 84 mm
gestation age 11 weeks 3 days to 13 weeks 6 days
Additional markers increase the detection rate and reduce false-positive rates:
tricuspid flow
Combining these factors with blood tests (i.e. beta HCG and pregnancy associated plasma protein-A) has been reported to achieve a nearly 95% detection rate for trisomies.
Apart from the screening protocol, early detection of major anomalies may be possible, and the checklist must include the following conditions:
limb reduction
open spina bifida
See also
References
- 1. Fong K, Toi A, Salem S et al. Detection of Fetal Structural Abnormalities with US during Early Pregnancy. RadioGraphics. 2004;24(1):157-174. doi:10.1148/rg.241035027
- 2. Kenkhuis M, Bakker M, Bardi F et al. Effectiveness of 12-13-week scan for early diagnosis of fetal congenital anomalies in the cell-free DNA era. Ultrasound Obstet Gynecol. 2018;51(4):463-469. doi:10.1002/uog.17487
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Related articles: Pathology: Genitourinary
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- fetal biometry
- amniotic fluid volume
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- 11-13 weeks antenatal scan
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