T2 weighted image
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At the time the article was created Jeremy Jones had no recorded disclosures.
View Jeremy Jones's current disclosuresAt the time the article was last revised Candace Makeda Moore had no financial relationships to ineligible companies to disclose.
View Candace Makeda Moore's current disclosures- T2WI
- T2W
- T2
- Fluid-sensitive sequence
T2 weighted image (T2WI) is one of the basic pulse sequences on MRI. The sequence weighting highlights differences on the T2 relaxation time of tissues.
Summary
repetition time (TR): long
echo time (TE): long
flip angle: less important than with T1 weighting
fat: intermediate-bright
fluid: bright
Physics
A T2WI relies upon the transverse relaxation (also known as "spin-spin" relaxation) of the net magnetization vector (NMV). T2 weighting tends to require long TE and TR times.
One way to think about T2 relaxation is as follows:
after an RF excitation pulse, there is relaxation of the spins from the transverse plane toward the main longitudinal magnetic vector (B0) - this is T1 weighting
at the same time, spins are decaying from their aligned precession in the transverse plane - differences in this decay are captured on T2 weighting
The amount of T2 decay a tissue experiences depends on multiple factors. Each tissue has an inherent T2 value, but external factors (such as magnetic field inhomogeneity) can decrease the T2 relaxation time. This additional effect is captured on T2*. The refocusing pulse on spin-echo sequences helps to mitigate these extraneous influences on the T2 relaxation time, trying to keep the image T2 weighted rather than T2* weighted.
Paramagnetic contrast agents (e.g. gadolinium-containing compounds) do not cause the same bright tissue contrast as they do on T1WI. Gadolinium shortens T2 relaxation time and actually results in hypointense signal.
If the TE is extended out over a very long time, only tissues with a very long T2 relaxation time will retain signal. This is the basis of MRCP.
References
- 1. Mitchell DG, Cohen M. MRI principles. Saunders. ISBN:0721600247. Read it at Google Books - Find it at Amazon
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