Atypical adenomatous hyperplasia of the lung
Atypical adenomatous hyperplasia (AAH) of the lung is a putative precursor lesion of adenocarcinoma of the lung. This entity replaces part of a spectrum of the previous bronchoalveolar carcinoma. It is defined as a peripheral focal proliferation of atypical cuboidal or columnar epithelial cells along the alveoli, alveolar septae and respiratory bronchioles 3,5. There is no significant destruction of alveolar walls 7.
Their radiographic appearances can be somewhat variable but have been commonly described as ground glass nodules 3-5.
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- 7. Kim HY, Shim YM, Lee KS et-al. Persistent pulmonary nodular ground-glass opacity at thin-section CT: histopathologic comparisons. Radiology. 2007;245 (1): 267-75. Radiology (full text) - doi:10.1148/radiol.2451061682 - Pubmed citation